Phosphorus pentachloride → 1-Acetyl-3-[1-chloro-1-(4-phthalimidomethyl-phenyl)-methylidene]-5-nitro-2-indolinone

HRID 24856Notes

Reaction equation

HRID 24856 reaction equation
O[C:2](=[C:21]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([N+:30]([O-:32])=[O:31])[CH:28]=2)[N:23]([C:33](=[O:35])[CH3:34])[C:22]1=[O:36])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]2[C:14](=[O:15])[C:13]3=[CH:16][CH:17]=[CH:18][CH:19]=[C:12]3[C:11]2=[O:20])=[CH:5][CH:4]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:38]>C1(C)C=CC=CC=1>[Cl:38][C:2](=[C:21]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([N+:30]([O-:32])=[O:31])[CH:28]=2)[N:23]([C:33](=[O:35])[CH3:34])[C:22]1=[O:36])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]2[C:14](=[O:15])[C:13]3=[CH:16][CH:17]=[CH:18][CH:19]=[C:12]3[C:11]2=[O:20])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 178473968HCID 178473968, compound

Product 1

HCID 697410191-Acetyl-3-[1-chloro-1-(4-phthalimidomethyl-phenyl)-methylidene]-5-nitro-2-indolinone

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Prepared analogously to Example 2b from 3-[1-hydroxy-1-(4-phthalimidomethyl-phenyl)-methylidene]-1-acetyl-5-nitro-2-indolinone and phosphorus pentachloride in toluene.

Sources & evidence

ORD record
ord-492d84e51df04bbead9ab77f3d38d2e9
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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