HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,4-Trichlorobenzene → 2,5-Dichlorobenzenethiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,4-Trichlorobenzene | HCID 13 | — |
| Reactant | Sodium hydrosulfide | HCID 28015 | — |
| Catalyst | Cupric acetate | HCID 8895 | — |
| Solvent | Ammonia | HCID 222 | — |
| Product | 2,5-Dichlorobenzenethiol | HCID 79965 | — |
Reaction Steps
the method in which 1,2,4-trichlorobenzene and sodium hydrosulfide are reacted in the presence of copper acetate catalyst in liquid ammonia solvent under increased pressure to yield 2,5-dichlorothiophenol, followed by reaction with monochloroacetic acid to yield 2,5-dichlorophenylthioglycolic acid [Kogyo Kagaku, 70, 1384 (1967)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05210287 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-5f609b4e76bc4b5bad749a0f11953275 |
| Source note | uspto-grants-1993_05 |