2-Cyano-4'-methylbiphenyl → HCID 14425662, compound

HRID 248619Notes

Reaction equation

HRID 248619 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=1)#[N:2].[CH3:16][Sn:17]([N:20]=[N+:21]=[N-:22])([CH3:19])[CH3:18]>C1(C)C=CC=CC=1>[CH3:16][Sn:17]([CH3:19])([CH3:18])[N:20]1[C:1]([C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[C:9]2[CH:10]=[CH:11][C:12]([CH3:15])=[CH:13][CH:14]=2)=[N:2][N:22]=[N:21]1

Participants

4

Reactant 2

HCID 1455122-Cyano-4'-methylbiphenylHCID 5104973Azido(trimethyl)stannane

Product 1

HCID 14425662HCID 14425662, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
70 °C

Procedure

A solution of 2-cyano-4'-methylbiphenyl (1.93 g) in toluene (25 mL) was treated with trimethyltin azide (2.65 g) and heated at reflux for 24 hours. The resulting suspension was cooled to 70° C. and filtered. The collected solid was dried at reduced pressure to give the title compound. 1H-NMR (CDCl3) δ 7.5 (m, 4H), 7.0 (q, 4H), 2.3 (s, 3H), 0.4 (s, 9H).

Workup

  1. temperatureheated
  2. temperatureat reflux for 24 hours
  3. filtrationfiltered
  4. customThe collected solid was dried at reduced pressure

Sources & evidence

ORD record
ord-55e87855af6e4b3bb08bb097e9edbeb2
Source dataset
uspto-grants-1993_05
Patent number
US05210211

Reaction notes

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