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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24864Generated: October 25, 2026

Acetaldehyde → (3Z)-3-[[4-(ethylaminomethyl)anilino]-phenylmethylidene]-5-nitro-1H-indol-2-one

https://huagongshe.com/reaction/24864

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetaldehydeHCID 177—
ReactantSodium cyanoborohydrideHCID 5003444—
ReactantHCID 178479182HCID 178479182—
SolventMethanolHCID 887—
Product(3Z)-3-[[4-(ethylaminomethyl)anilino]-phenylmethylidene]-5-nitro-1H-indol-2-oneHCID 178463713—

Reaction Steps

Prepared analogously to Example 159 from (Z)-3-[1-(4-aminomethyl-phenylamino)-1-phenyl-methylidene]-5-nitro-2-indolinone-hydrochloride, acetaldehyde and sodium cyanoborohydride in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855710B2
Source datasetuspto-grants-2005_02
ORD IDord-e9868bc418e349dbab10b8ecd3276bcd
Source noteuspto-grants-2005_02