HRID24878

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

$结构：CCOC(=O)C1CCN(Cc2ccc(N/C(=C3\C(=O)Nc4ccc([N+](=O)[O-])cc43)c3ccccc3)cc2)CC1$

HCID178469212

未命名化合物

PRODUCTS

生成物

结构：O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C(/Nc1ccc(CN2CCC(C(=O)O)CC2)cc1)c1ccccc1

HCID178517268

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Prepared analogously to Example 8 by saponification of (Z)-3-{1-[4-(4-ethoxycarbonylpiperidinomethyl)-phenylamino]-1-phenyl-methylidene}-5-nitro-2-indolinone with sodium hydroxide solution in ethanol.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2a146ccca13b4023bbae66af4b57589b
来源数据集: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06855710B2
来源说明: uspto-grants-2005_02

反应 SMILES

C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([NH:19]/[C:20](=[C:27]3\[C:28](=[O:39])[NH:29][C:30]4[C:35]\3=[CH:34][C:33]([N+:36]([O-:38])=[O:37])=[CH:32][CH:31]=4)/[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[CH:15][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])C.[OH-].[Na+]>C(O)C>[C:4]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][C:13]2[CH:14]=[CH:15][C:16]([NH:19]/[C:20](=[C:27]3\[C:28](=[O:39])[NH:29][C:30]4[C:35]\3=[CH:34][C:33]([N+:36]([O-:38])=[O:37])=[CH:32][CH:31]=4)/[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[CH:17][CH:18]=2)[CH2:8][CH2:7]1)([OH:5])=[O:3]