Sodium Hydroxide → HCID 178517268, compound

HRID 24878Notes

Reaction equation

HRID 24878 reaction equation
C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([NH:19]/[C:20](=[C:27]3\[C:28](=[O:39])[NH:29][C:30]4[C:35]\3=[CH:34][C:33]([N+:36]([O-:38])=[O:37])=[CH:32][CH:31]=4)/[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[CH:15][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])C.[OH-].[Na+]>C(O)C>[C:4]([CH:6]1[CH2:11][CH2:10][N:9]([CH2:12][C:13]2[CH:14]=[CH:15][C:16]([NH:19]/[C:20](=[C:27]3\[C:28](=[O:39])[NH:29][C:30]4[C:35]\3=[CH:34][C:33]([N+:36]([O-:38])=[O:37])=[CH:32][CH:31]=4)/[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[CH:17][CH:18]=2)[CH2:8][CH2:7]1)([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178469212HCID 178469212, compound

Product 1

HCID 178517268HCID 178517268, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 8 by saponification of (Z)-3-{1-[4-(4-ethoxycarbonylpiperidinomethyl)-phenylamino]-1-phenyl-methylidene}-5-nitro-2-indolinone with sodium hydroxide solution in ethanol.

Sources & evidence

ORD record
ord-2a146ccca13b4023bbae66af4b57589b
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

Loading…