反应详情

A solution of 100.0 grams (0.599 mol) of 2-bromoethyl acetate, 47.37 grams (0.599 mol) of pyridine and 300 milliters of acetonitrile was heated at reflux for 19 hours and then cooled, concentrated on a rotovap to an oil, heated in methyl ethyl ketone and then cooled. On prolonged standing, solid crystallized, was collected and dried. The yield of product was 129.5 grams (87.85% of theory); mp=69°-74° C.

1. temperatureat reflux for 19 hours
2. temperaturecooled
3. concentrationconcentrated on a rotovap to an oil
4. temperatureheated in methyl ethyl ketone
5. temperaturecooled
6. customcrystallized
7. customwas collected
8. customdried