HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridin-4-YL-acrylic acid methyl ester → Methyl 3-(4-pyridyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridin-4-YL-acrylic acid methyl ester | HCID 98163 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-(4-pyridyl)propanoate | HCID 3704115 | — |
Reaction Steps
Methyl 3-(4-pyridinyl)propenoate (7.00 grams) and 10% palladium on carbon (1.00 gram) were vigorously stirred in methanol (70 mL) at room temperature under a hydrogen atmosphere for 5 hours. The catalyst was removed by filtration through a filter aide, and the filtrate was evaporated in vacuo. The crude product was purified by distillation in a kugelrohr apparatus. Yield: 5.14 grams (73%). Bp: 125° C. (oven temperature) at 0.6 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05212169 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-b069747be25c4f4e8fd7969622b7dc70 |
| Source note | uspto-grants-1993_05 |