2,3-Dihydroxybutanedioic Acid → HCID 131717917, compound

HRID 248882Notes

Reaction equation

HRID 248882 reaction equation
[CH2:1]([N:3]([N:6]([S:27]([N:30]([C@H:36]1[CH2:50][C@H:49]2[C@@H:39]([CH2:40][C:41]3[C:51]4[C:44](=[CH:45][CH:46]=[CH:47][C:48]2=4)[NH:43][C:42]=3[CH3:52])[N:38]([CH2:53][CH2:54][CH3:55])[CH2:37]1)[N:31]([CH2:34]C)[CH2:32]C)(=[O:29])=[O:28])[C@H:7]1[CH2:21][C@H:20]2[C@@H:10]([CH2:11][C:12]3[C:22]4[C:15](=[CH:16][CH:17]=[CH:18][C:19]2=4)[NH:14][C:13]=3[CH3:23])[N:9]([CH2:24][CH2:25][CH3:26])[CH2:8]1)[CH2:4]C)C.C(O)(=O)C(C(C(O)=O)O)O>CO>[CH3:32][N:31]([N:30]([S:27]([N:6]([C@H:7]1[CH2:21][C@H:20]2[C@@H:10]([CH2:11][C:12]3[C:22]4[C:15](=[CH:16][CH:17]=[CH:18][C:19]2=4)[NH:14][C:13]=3[CH3:23])[N:9]([CH2:24][CH2:25][CH3:26])[CH2:8]1)[N:3]([CH3:1])[CH3:4])(=[O:28])=[O:29])[C@H:36]1[CH2:50][C@H:49]2[C@@H:39]([CH2:40][C:41]3[C:51]4[C:44](=[CH:45][CH:46]=[CH:47][C:48]2=4)[NH:43][C:42]=3[CH3:52])[N:38]([CH2:53][CH2:54][CH3:55])[CH2:37]1)[CH3:34]

Participants

4

Reactant 2

HCID 8752,3-Dihydroxybutanedioic AcidHCID 131717918HCID 131717918, compound

Product 1

HCID 131717917HCID 131717917, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Analogously, there is produced with diethylaminosulfonic acid chloride: (diethylamino)-(2-methyl-6-n-propyl-8alpha-ergolinylamino)-sulfone. Yield 25% as tartaric acid salt, [α]D =-34° (0.5% in methanol).

Sources & evidence

ORD record
ord-f674eb7c703843dfa205ec8cdaddc96c
Source dataset
uspto-grants-1993_05
Patent number
US05212178

Reaction notes

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