HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 18946962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | HCID 18946596 | HCID 18946596 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18946962 | HCID 18946962 | — |
Reaction Steps
To a solution of methyl 2-(n-butyl)indole-7-carboxylate (P) (0.3 g) in 6 ml of dimethylformamide at room temperature was added N-chlorosuccinimide (0.17 g). The solution was stirred at room temperature for 16 hours, then water was added, and the mixture extracted with ether. The extract was separated and solvent evaporated under reduced pressure, to give methyl 2-(n-butyl)-3-chloroindole-7-carboxylate, a compound of Formula (Q) where X is chloro, as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05212195 |
| Source dataset | uspto-grants-1993_05 |
| ORD ID | ord-eedd5e3566654d119eb69e0350119f7d |
| Source note | uspto-grants-1993_05 |