Sodium Hydroxide → HCID 178505131, compound

HRID 24894Notes

Reaction equation

HRID 24894 reaction equation
C([O:3][C:4]([CH2:6][N:7]([C:12]1[CH:17]=[CH:16][C:15]([NH:18]/[C:19](=[C:26]2\[C:27](=[O:38])[NH:28][C:29]3[C:34]\2=[CH:33][C:32]([N+:35]([O-:37])=[O:36])=[CH:31][CH:30]=3)/[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:14][CH:13]=1)[S:8]([CH3:11])(=[O:10])=[O:9])=[O:5])C.[OH-].[Na+]>O1CCOCC1>[C:4]([CH2:6][N:7]([C:12]1[CH:13]=[CH:14][C:15]([NH:18]/[C:19](=[C:26]2\[C:27](=[O:38])[NH:28][C:29]3[C:34]\2=[CH:33][C:32]([N+:35]([O-:37])=[O:36])=[CH:31][CH:30]=3)/[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:16][CH:17]=1)[S:8]([CH3:11])(=[O:10])=[O:9])([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178472670HCID 178472670, compound

Product 1

HCID 178505131HCID 178505131, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Prepared analogously to Example 8 by saponification of (Z)-3-{1-[4-(N-ethoxycarbonylmethyl-N-methylsulphonyl-amino)-phenylamino]-1-phenyl-methylidene}-5-nitro-2-indolinone with sodium hydroxide solution in dioxane.

Sources & evidence

ORD record
ord-e824554ffb894a408a7abdc4078a2faf
Source dataset
uspto-grants-2005_02
Patent number
US06855710B2

Reaction notes

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