1,1'-Carbonyldiimidazole → HCID 178483446, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 63, using 0.9 g (2.5 mmol) of N-[3-(4-chlorophenyl)-3-(2-pyridyl)propyl]-N-methyl-1,6-hexanediamine, an equimolar amount of 1,1'-carbonyldiimidazole and 0.6 g (2.6 mmol) of 2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethaneamine as starting materials. Working up by chromatography (eluant: methylene chloride) analogously to Example 63 yields the purified title compound in the form of an oil; MS (+FAB method): m/z (rel. int.[%])=617 ([M+H]+, 6), 230 (100), 155 (28); IR (KBr): 1641 cm-1 (C=O).

Provenance & Evidence