1,1'-Carbonyldiimidazole → HCID 178483436, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 63, using 0.9 g (2.5 mmol) of N-[3-(4-fluorophenyl)-3-(2-pyridyl)propyl]-N-methyl-1,7-heptanediamine, an equimolar amount of 1,1'-carbonyldiimidazole and 0.65 g (2.8 mmol) of 2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethaneamine as starting materials. Working up by chromatography (eluant: methylene chloride) analogously to Example 63 yields the purified title compound in the form of a dry foam; MS (+FAB method): m/z (rel. int.[%])=615 ([M+H]+ 2), 214 (100); IR (KBr): 1632 cm-1 (C=O).

Provenance & Evidence