1,1'-Carbonyldiimidazole → HCID 19762547, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 63, using 0.54 g (1.65 mmol) of N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,3-propanediamine and the equimolar amounts of 1,1'-carbonyldiimidazole and 3-[3-(piperidinomethyl)phenoxy]propylamine as starting materials. Working up by chromatography analogously to Example 63 yields the purified title compound in the form of a viscous oil; MS (+FAB method): m/z (rel. int. [%])=603 ([M+H]+, 10), 121 (100); IR (KBr): 1639 cm-1 (C=O). For further analysis, a portion of the compound is converted into the O,O'-ditoluoyltartaric acid salt and recrystallised from isopropanol/ether; m.p.: 120° C. (isopropanol/ether).

Provenance & Evidence