N-[2-[N-(4-fluorobenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,3-propanediamine → HCID 178483803, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 1, using 0.53 g (1.67 mmol) of N-[2-[N-(4-fluorobenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,3-propanediamine and the equimolar amount of N-cyano-N'-[2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethyl]-O-phenyl-isourea as starting materials. Working up by chromatography analogously to Example 1 yields the purified title compound in the form of a viscous oil. MS (+FAB method): m/z (rel. int. [%])=598 ([M+H]+, 6), 109 (100); IR (KBr): 2163 cm-1 (C≡N); C27H36FN11S2 (597.80).

Provenance & Evidence