1,1'-Carbonyldiimidazole → HCID 178491104, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 63, using 0.54 g (1.58 mmol) of N-[2-[N-(4-methoxybenzyl)-N-(2-pyridyl)amino]ethyl]-N-methyl-1,4-butanediamine and the equimolar amounts of 1,1'-carbonyldiimidazole and 2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethaneamine as starting materials. Working up by chromatography analogously to Example 63 yields the purified title compound in the form of a viscous oil; MS (+FAB method): m/z (rel. int. [%])=600 ([M+H]+, 1), 121 (100); IR (KBr): 1599 cm-1 (C=O). For further analysis, a portion of the compound is converted into the picric acid salt and recrystallised from ethanol; m.p.: 104°-106° C. (ethanol).

Provenance & Evidence