1,1'-Carbonyldiimidazole → HCID 178483550, compound

Participants

Reaction Steps

Preparation is effected analogously to Example 63, using 0.37 g (1.2 mmol) of N-[2-(diphenylmethoxy)ethyl]-N-methyl-1,4-butanediamine and the equimolar amounts of 1,1'-carbonyldiimidazole and 2-[[(2-guanidino-4-thiazolyl)methyl]thio]ethaneamine as starting materials. Working up by chromatography analogously to Example 63 yields the purified title compound in the form of a viscous oil; MS (+FAB method): m/z (rel. int. [%])=570 ([M+H]+, 11), 167 (100); IR (KBr): 1644 cm-1 (C=O). For further analysis, a portion of the compound is converted into the tartaric acid salt and recrystallised from acetonitrile/isopropanol/petroleum ether; m.p.: 101° C. (acetonitrile/isopropanol/petroleum ether).

Provenance & Evidence