反应详情

In a round bottom flask, there are introduced 200 ml of thionyl chloride and there are then added, in small fractions, 35 g (122 mmoles) of the acid obtained in stage (a), above. The reaction mixture is heated to reflux until the emission of gases ceases. The reaction mixture is evaporated to dryness, taken up in 100 ml of anhydrous benzene and again evaporated to dryness, yielding 37 g of the expected product (100% yield) having a melting point of 153°-154° C.

1. temperatureThe reaction mixture is heated
2. temperatureto reflux until the emission of gases ceases
3. customThe reaction mixture is evaporated to dryness
4. customagain evaporated to dryness