HCID 53721982, compound → HCID 178512865, compound

HRID 249072Notes

Reaction equation

HRID 249072 reaction equation
Cl.[CH2:2]([O:9][CH2:10][C@@H:11]([C:13]([NH:15][C@H:16]([C:21]([N:23]1[CH2:41][CH2:40][CH2:39][C@H:24]1[C:25]([NH:27][C@H:28]([C:36]([OH:38])=[O:37])[CH2:29][CH2:30][CH2:31][NH:32][C:33](=[NH:35])[NH2:34])=[O:26])=[O:22])[CH2:17][C:18](=[O:20])[OH:19])=[O:14])[NH2:12])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[N+](C1C=CC(O[C:52](=[O:76])[C@H:53]([CH:65](CC2C=CC=CC=2)[C:66]([OH:68])=[O:67])[NH:54][C:55]([O:57][CH2:58][C:59]2[CH:64]=[CH:63][CH:62]=[CH:61][CH:60]=2)=[O:56])=CC=1)([O-])=O>>[C:55]([NH:54][C@H:53]([C:52]([NH:12][C@H:11]([C:13]([NH:15][C@H:16]([C:21]([N:23]1[CH2:41][CH2:40][CH2:39][C@H:24]1[C:25]([NH:27][C@H:28]([C:36]([OH:38])=[O:37])[CH2:29][CH2:30][CH2:31][NH:32][C:33](=[NH:34])[NH2:35])=[O:26])=[O:22])[CH2:17][C:18](=[O:19])[OH:20])=[O:14])[CH2:10][O:9][CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1)=[O:76])[CH2:65][C:66](=[O:67])[O:68][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)([O:57][CH2:58][C:59]1[CH:60]=[CH:61][CH:62]=[CH:63][CH:64]=1)=[O:56]

Participants

3

Reactant 2

HCID 53721982HCID 53721982, compoundHCID 178479454HCID 178479454, compound

Product 1

HCID 178512865HCID 178512865, compound

Procedure

A method which comprises reacting O-benzyl-L-seryl-L-aspartyl-L-prolyl-L-arginine hydrochloride with N-carbobenzoxy-β-benzyl-L-aspartic acid p-nitrophenyl ester to give N-carbobenzoxy-O-benzyl-L-aspartyl-O-benzyl-L-seryl-L-aspartyl-L-prolyl-L-arginine.

Sources & evidence

ORD record
ord-2115d9c6868b42c4be94544428ad3c38
Source dataset
uspto-grants-1993_05
Patent number
US05212287

Reaction notes

Loading…