HCID 53721982, compound → HCID 178512866, compound

HRID 249073Notes

Reaction equation

HRID 249073 reaction equation
Cl.[NH2:2][C@H:3]([C:6]([NH:8][C@H:9]([C:14]([N:16]1[CH2:34][CH2:33][CH2:32][C@H:17]1[C:18]([NH:20][C@H:21]([C:29]([OH:31])=[O:30])[CH2:22][CH2:23][CH2:24][NH:25][C:26](=[NH:28])[NH2:27])=[O:19])=[O:15])[CH2:10][C:11](=[O:13])[OH:12])=[O:7])[CH2:4][OH:5].[N+](C1C=CC(O[C:45](=[O:69])[C@H:46]([CH:58](CC2C=CC=CC=2)[C:59]([OH:61])=[O:60])[NH:47][C:48]([O:50][CH2:51][C:52]2[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=2)=[O:49])=CC=1)([O-])=O>>[C:48]([NH:47][C@H:46]([C:45]([NH:2][C@H:3]([C:6]([NH:8][C@H:9]([C:14]([N:16]1[CH2:34][CH2:33][CH2:32][C@H:17]1[C:18]([NH:20][C@H:21]([C:29]([OH:31])=[O:30])[CH2:22][CH2:23][CH2:24][NH:25][C:26](=[NH:27])[NH2:28])=[O:19])=[O:15])[CH2:10][C:11](=[O:12])[OH:13])=[O:7])[CH2:4][OH:5])=[O:69])[CH2:58][C:59](=[O:60])[O:61][CH2:51][C:52]1[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=1)([O:50][CH2:51][C:52]1[CH:53]=[CH:54][CH:55]=[CH:56][CH:57]=1)=[O:49]

Participants

3

Reactant 2

HCID 53721982HCID 53721982, compoundHCID 178479455HCID 178479455, compound

Product 1

HCID 178512866HCID 178512866, compound

Procedure

A method which comprises reacting L-seryl-L-aspartyl-L-prolyl-L-arginine hydrochloride with N-carbobenzoxy-β-benzyl-L-aspartic acid p-nitrophenyl ester to give N-carbobenzoxy-O-benzyl-L-aspartyl-L-seryl-L-aspartyl-L-prolyl-L-arginine.

Sources & evidence

ORD record
ord-f86a5af01fe243a89922eb5702b93345
Source dataset
uspto-grants-1993_05
Patent number
US05212287

Reaction notes

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