HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249084Generated: October 29, 2026
Sulfuric Acid → 5-Acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
https://huagongshe.com/reaction/249084
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 5-Acetyl-2-hydroxy-6-methylnicotinonitrile | HCID 2765476 | — |
| Product | 5-Acetyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide | HCID 2764417 | — |
Reaction Steps
To 100 grams of concentrated sulfuric acid is added 10 g (0.056 mole) of 5-acetyl-1,2-dihydro-6-methyl2-oxo-3-pyridinecarbonitrile. The mixture is stirred at 60° C. for 5 hours, cooled and then poured on 1 kg ice. The resulting solid is collected, washed with water and recrystallized from ethanol to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05212314 |
|---|
| Source dataset | uspto-grants-1993_05 |
|---|
| ORD ID | ord-9a931bb715594d5fb802a2e3d32f45a5 |
|---|
| Source note | uspto-grants-1993_05 |
|---|
