3-(2-Methylpropenyl)benzonitrile → 3-Isobutylbenzonitrile
Reaction equation
[CH3:1][C:2]([CH3:12])=[CH:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[C:7]#[N:8]>CO.[Pd]>[CH2:3]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[C:7]#[N:8])[CH:2]([CH3:12])[CH3:1]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 25 °C
Procedure
To a solution of 3-(2-methyl-1-propenyl)benzonitrile (5.80 g) in methanol (50 ml) was added 10% palladium on activated carbon (1 g), and the mixture was stirred under hydrogen atmosphere (3 atm) at 25° C. for 1 hour. The catalyst was filtered off and the filtrate was evaporated to give 3-isobutylbenzonitrile (5.52 g) as a pale yellow oil.
Workup
- filtrationThe catalyst was filtered off
- customthe filtrate was evaporated
Sources & evidence
- ORD record
- ord-d6481656cfa043db90ae1011ec48aef2
- Source dataset
- uspto-grants-1993_05
- Patent number
- US05212320
Reaction notes
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