HCID 18651942, compound → (-)-(2S,3R)-2,3-epoxy-8-methyl-1-nonanol

HRID 249238Notes

Reaction equation

HRID 249238 reaction equation
C([O:6][CH2:7][C@@H:8]1[O:17][C@@H:9]1[CH2:10][CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])(=O)CCC.[OH-].[K+].CO>>[O:17]1[C@H:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[C@@H:8]1[CH2:7][OH:6]

Participants

3

Reactant 2

HCID 18651942HCID 18651942, compoundHCID 23689386Potassium hydroxide methanol

Product 1

HCID 14102158(-)-(2S,3R)-2,3-epoxy-8-methyl-1-nonanolYield 93.8%

Procedure

3.6 g of (-)-(2S,3R)-1-butyroxy-2,3-epoxy-8-methylnonane was hydrolyzed with potassium hydroxide/methanol to yield 2.4 g of (-)-(2S,3R)-2,3-epoxy-8-methyl-1-nonanol.

Sources & evidence

ORD record
ord-4176ab5b2d544d5ebf274ed33664a499
Source dataset
uspto-grants-1993_05
Patent number
US05213975

Reaction notes

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