反应详情

A solution of 24 g of 2-methylanisole, 35 g of N-bromosuccinimide and 1.24 g of dibenzoyl peroxide in 150 ml of carbon tetrachloride was heated to boiling under reflux for 12 hours. After cooling the solution was filtered and the filtrate is evaporated. The residue was recrystallized from hexane. There were obtained 18.6 g (47%) of 4-bromo-2-methylanisole as a colorless solid; m.p. 66°-68°.

1. temperatureunder reflux for 12 hours
2. temperatureAfter cooling the solution
3. filtrationwas filtered
4. customthe filtrate is evaporated
5. customThe residue was recrystallized from hexane