Methanol → HCID 24839018, compound

HRID 249336Notes

Reaction equation

HRID 249336 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH:6]([CH2:11][NH2:12])[CH2:7][C:8](Cl)=[O:9].[CH3:13][OH:14]>N1C=CC=CC=1>[CH3:13][O:14][C:8](=[O:9])[CH2:7][CH:6]([C:2]1[NH:1][CH:5]=[CH:4][N:3]=1)[CH2:11][NH2:12]

Participants

4

Reactant 2

HCID 887MethanolHCID 54532498HCID 54532498, compound

Product 1

HCID 24839018HCID 24839018, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.01 mol of the compound obtained in stage A of Example 16 is dissolved in 30 cm3 of pyridine. 1 cm3 of methanol is added. The whole is heated under reflux for five hours, the reaction medium is evaporated in vacuo on a water bath. The residue is dried and purified by chromatography.

Workup

  1. temperatureThe whole is heated
  2. temperatureunder reflux for five hours
  3. customthe reaction medium is evaporated in vacuo on a water bath
  4. customThe residue is dried
  5. custompurified by chromatography

Sources & evidence

ORD record
ord-7e4a88fe31d64bce938a95b0f3dccbde
Source dataset
uspto-grants-1993_05
Patent number
US05214063

Reaction notes

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