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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249387Generated: October 29, 2026

Water → HCID 19088718, compound

https://huagongshe.com/reaction/249387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantHCID 19769486HCID 19769486—
ReactantAluminium lithium hydrideHCID 21226445—
SolventDiethyl EtherHCID 3283—
ProductHCID 19088718HCID 19088718—

Reaction Steps

Lithium aluminium hydride (0.345 g) was added to a solution of the ester so obtained in diethyl ether (70 ml) and the mixture was stirred at ambient temperature for 1 hour. Water (10 ml) was added dropwise and the mixture was filtered. The organic layer was dried (MgSO4) and evaporated to give (-)-2-(3-benzyloxy-5-fluorophenyl)butane-1,2-diol (2.2 g), as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05214069
Source datasetuspto-grants-1993_05
ORD IDord-c257404c875d4618a19549a18f0f98f8
Source noteuspto-grants-1993_05