참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | DL-Arabinose | HCID 854 | — |
| 반응물 | L-Lysine | HCID 5962 | — |
| 반응물 | Aldehydo-D-ribose | HCID 5311110 | — |
| 반응물 | HCID 178418600 | HCID 178418600 | — |
| 생성물 | Pentosidine | HCID 119593 | — |
반응 단계
In order to confirm the pentose-derived nature of the native fluorophore 100 mM each of L-lysine, L-arginine and D-ribose were heated for 1 hour at 80° C. Injection of a small amount of this synthetic material on HPLC revealed a major fluorescent peak co-eluting with the native fluorophore. (see FIG. 5) In order to substantiate the proposed structure, the synthetic fluorophore was prepared preparatively and purified. Total yield was 21 mg; i.e., 0.02% of the reactants.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05214138 |
|---|
| 출처 데이터셋 | uspto-grants-1993_05 |
|---|
| ORD ID | ord-bffb7174a0ac4af9a4dc20f013edb573 |
|---|
| 출처 메모 | uspto-grants-1993_05 |
|---|
