Lithium Hydroxide → HCID 67847834, compound

Participants

Reaction Steps

A solution of 2.66 g (5 mmol) of the resultant compound of Example 170 in 60 mL of tetrahydrofuran was cooled to 0° C., treated with 0.63 g (15 mmol) of LiOH in 30 mL of H2O and allowed to stir for 2 h. After concentration of the solvent, the mixture was partitioned between H2O and ether, acidified, extracted with ethyl acetate, dried over MgSO4 and concentrated to give 1.55 g (70%) of the desired compound.

Provenance & Evidence