反应详情

1.4 g (6.7 mmol) of 4-(2-dimethylamino-ethylamino)-nitrobenzene (Example 326a) are refluxed for 4 hours in 20 ml of formic acid. Then the solvent is eliminated in vacuo, the residue taken up in water and combined with 2 N sodium hydroxide solution until an alkaline reaction is obtained. The mixture is extracted with ethyl acetate, the combined organic phases are dried over magnesium sulphate and the solvent is eliminated in vacuo. The product is obtained as an oil.

1. customis obtained
2. extractionThe mixture is extracted with ethyl acetate
3. dry with materialthe combined organic phases are dried over magnesium sulphate
4. customThe product is obtained as an oil