反应详情

In 100 ml of CHCl3 was dissolved 6.39 g (0.052 mole) of 2-(3-pyridyl)ethanol followed by dropwise addition of 15.6 ml of thionyl chloride with stirring at room temperature. Then, the mixture was stirred for 1.5 hours, after which the solvent was distilled off. After addition of ether, crystals were recovered by filtration and dried. The procedure gave 9.13 g of 2-(3-pyridyl)ethyl chloride hydrochloride as white crystals.

1. stirringThen, the mixture was stirred for 1.5 hours
2. distillationafter which the solvent was distilled off
3. additionAfter addition of ether, crystals
4. filtrationwere recovered by filtration
5. customdried