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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249503Generated: October 28, 2026

2-[(6-Chloropyridin-3-yl)methyl]-1H-isoindole-1,3(2H)-dione → 1-(6-Bromopyridin-3-yl)methanamine

https://huagongshe.com/reaction/249503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(6-Chloropyridin-3-yl)methyl]-1H-isoindole-1,3(2H)-dioneHCID 14324713—
Reactant2-[(6-Bromo-3-pyridinyl)methyl]-1H-isoindole-1,3(2H)-dioneHCID 22450510—
Product1-(6-Bromopyridin-3-yl)methanamineHCID 22450529—

Reaction Steps

The reaction procedure of Reference Example 3 was repeated except that N-(6-bromo-3-pyridylmethyl)phthalimide was used in lieu of N-(6-chloro-3-pyridylmethyl)phthalimide, to give the title compound as pale yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05214152
Source datasetuspto-grants-1993_05
ORD IDord-094ca71fdfd04b0bb98d14edf6725452
Source noteuspto-grants-1993_05