HRID249683

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID268963

Ethyl 4-Chloroquinoline-3-carboxylate

C12H10ClNO2

HCID178469538

未命名化合物

PRODUCTS

生成物

HCID4322147

Ethyl 4-chloro-6-(trifluoromethyl)quinoline-3-carboxylate

C13H9ClF3NO2

PROCEDURE

实验过程

The title compound was prepared following the procedure described in Step 2 for the synthesis of 3a using 2h instead of 2a. 1H NMR (CDCl3) δ (ppm): 1.46 (3H, t, J=7.14 Hz), 4.51 (2H, q, J=7.14 Hz), 8.00 (1H, dd, J=8.79, 1.92 Hz), 8.26 (1H, d, J=8.79 Hz), 8.78 (1H, dd, J=1.92, 0.83 Hz), 9.34 (1H, s). m/z 304.6 (MH+).