反应详情

A mixture of 4.84 g dimethyl-4-nitroindane-2,2-dicarboxylate (0.0167 mol), 0.84 g lithium chloride (0.0198 mol), 1.1 mL water, and 18 mL dimethylsulfoxide was heated to 160 C under nitrogen for two hours. It was then allowed to cool and the dimethylsulfoxide was removed under high vacuum. The residue was purified on silica (10%-100% CH2Cl2 in hexanes) to give 2.5 g white solid (65%).

1. temperaturewas heated to 160 C under nitrogen for two hours
2. temperatureto cool
3. customthe dimethylsulfoxide was removed under high vacuum
4. customThe residue was purified on silica (10%-100% CH2Cl2 in hexanes)