反应详情

To a 7.0 M solution of ammonia in methanol (32 mL) was dropwise added 1-isocyanatopentane (5.0 g, 0.044 mol). After the addition, the mixture was stirred at room temperature for 1 h and concentrated under reduced pressure to give a white solid, which was directly used for next step without further purification. LCMS calculated for C6H15N2O (M+H): 131.1. found 131.1.

1. additionAfter the addition
2. concentrationconcentrated under reduced pressure
3. customto give a white solid, which
4. customwas directly used for next step without further purification