反应详情

温度

100 °C

7-Benzyl-6-(methylthio)-3-pentyl-3,7-dihydro-2H-purin-2-one (1.2 g, 3.5 mmol) and hydrazine (10 mL, 100 mmol) were mixed. After being stirred at 100° C. overnight, the solution was concentrated in vacuum. The residue was dissolved in DMSO and purified using preparative LCMS. The product fractions were collected and lyophilized to provide the product as a white powder (0.56 g, 60% yield). LCMS calculated for C17H23N6O (M+H): 327.2. found: 327.1.

1. concentrationthe solution was concentrated in vacuum
2. dissolutionThe residue was dissolved in DMSO
3. custompurified
4. customThe product fractions were collected