참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Lithium hydroxide, monohydrate | HCID 168937 | — |
| 반응물 | Methyl 2-thioxo-2,3-dihydrobenzoxazole-4-carboxylate | HCID 22272869 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Lithium 2-thioxo-2,3-dihydrobenzoxazole-4-carboxylate | HCID 86623720 | 96.5% |
반응 단계
To a solution of methyl 2-thioxo-2,3-dihydrobenzoxazole-4-carboxylate (150 mg, 0.72 mmol) in THF (6 mL) was added a solution of lithium hydroxide monohydrate (45.1 mg, 1.08 mmol) in H2O (3 mL). The reaction mixture was heated to 75° C. with stirring for 3 days, cooled down to room temperature and concentrated under reduced pressure to afford the lithium 2-thioxo-2,3-dihydrobenzoxazole-4-carboxylate (135 mg, 96.5%) as a yellow solid. MS consistent
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07863271B2 |
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| 출처 데이터셋 | uspto-grants-2011_01 |
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| ORD ID | ord-594f69d80b204df6a9ebf4a3bc0545bc |
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| 출처 메모 | uspto-grants-2011_01 |
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