HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → HCID 52941871, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride | HCID 12494973 | — |
| Reactant | HCID 66873286 | HCID 66873286 | — |
| Product | HCID 52941871 | HCID 52941871 | — |
Reaction Steps
Following general procedure GP-C1, a mixture of lithium 2-(isopropyl(methyl)amino)benzoxazole-4-carboxylate and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to afford (S)—N-(quinuclidine-8-yl)-2-(isopropyl(methyl)amino)benzoxazole-4-carboxamide which was converted to the hydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863271B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-ee7b3f3d3e0f430893958a28574a7f52 |
| Source note | uspto-grants-2011_01 |