HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → HCID 66874275, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride | HCID 12494973 | — |
| Reactant | HCID 66874132 | HCID 66874132 | — |
| Product | HCID 66874275 | HCID 66874275 | — |
Reaction Steps
Following general procedure GP-C1, lithium 2-(dimethylamino)-6-chlorobenzoxazole-4-carboxylate and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to provide (S)—N-(quinuclidine-8-yl)-6-chloro-2-(dimethylamino)benzoxazole-4-carboxamide, which was converted to the hydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863271B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-c01e52e7656a4b46830933ed3b7b6f23 |
| Source note | uspto-grants-2011_01 |