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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249903Generated: October 30, 2026

(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → HCID 52949186, compound

https://huagongshe.com/reaction/249903

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochlorideHCID 12494973—
ReactantHCID 66873632HCID 66873632—
ProductHCID 52949186HCID 52949186—

Reaction Steps

Following general procedure GP-C2, lithium 2-(diethylamino)benzoxazole-4-carboxylate and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to provide (S)—N-(quinuclidine-8-yl)-2-diethylaminobenzoxazole-4-carboxamide, which was converted to the hydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07863271B2
Source datasetuspto-grants-2011_01
ORD IDord-09992d03c1b841a69894833f66605c02
Source noteuspto-grants-2011_01