HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride → HCID 66874198, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-1-azabicyclo[2.2.2]octan-3-amine dihydrochloride | HCID 12494973 | — |
| Reactant | HCID 66873820 | HCID 66873820 | — |
| Product | HCID 66874198 | HCID 66874198 | — |
Reaction Steps
Following the general procedure GP-C2, a mixture of 2-((2S,6S)-4-benzyl-2,6-dimethyl-3-oxopiperazine-1-yl)benzoxazole-4-carboxylic acid and (S)-(−)-3-aminoquinuclidine dihydrochloride were coupled to provide (S)—N-(quinuclidine-8-yl) 2-((2S,6S)-4-benzyl-2,6-dimethyl-3-oxopiperazine-1-yl)benzoxazole-4-carboxamide which was converted to the hydrochloride salt following general procedure GP-D1. 1H NMR and MS consistent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863271B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-e93c2115ada54fe29e31c9b04c310ef9 |
| Source note | uspto-grants-2011_01 |