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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24999Generated: November 1, 2026

Hydrochloric Acid → HCID 12132292, compound

https://huagongshe.com/reaction/24999

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 4-(4-(2-methoxybenzyloxy)phenyl)-4-oxobutyrateHCID 21964526—
SolventEthanolHCID 702—
ProductHCID 12132292HCID 12132292—

Reaction Steps

A solution of Ethyl 4-(4-(2-methoxybenzyloxy)phenyl)-4-oxobutyrate (Step B, 1.49 g, 4.3 mmol) in abs ethanol (20 ml) was treated with 1N NaOH (6 ml). The reaction mixture was stirred at room temperature for 2 hours and then acidified with 1M HCl. The resulting white solid was filtered, washed with cold water and dried under vacuum to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06858602B2
Source datasetuspto-grants-2005_02
ORD IDord-2fa665c32bba4a0fb585a67bdba37e8a
Source noteuspto-grants-2005_02