HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 249990Generated: October 26, 2026
Citraconic Anhydrides → 3-Bromo-4-methyl-2,5-dihydrofuran-2,5-dione
https://huagongshe.com/reaction/249990
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Citraconic Anhydrides | HCID 12012 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Aluminum bromide | HCID 24409 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Bromo-4-methyl-2,5-dihydrofuran-2,5-dione | HCID 10583854 | 9,023.2% |
Reaction Steps
A mixture of 3-methyl-2,5-furandione (citraconic anhydride, 1 g), AlBr3 (26 mg) and Br2 (0.46 mL) was heated at 120° C. overnight. Ethyl acetate was then added and the organic phase was washed with HCl 0.1% and then with brine. The organic phase was dried and concentrated in vacuo to give the crude product (1.680 g) that was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07863299B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-7740d3fce82847729128eaba9969fa7f |
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| Source note | uspto-grants-2011_01 |
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