HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 250161Generated: October 31, 2026
4-Hydroxybenzaldehyde → 4-[2-(5-Ethyl-2-pyridinyl)-2-hydroxyethoxy]benzaldehyde
https://huagongshe.com/reaction/250161
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | 4-(5-Ethylpyridin-2-yl)-1,3,2lambda~4~-dioxathiolan-2-one | HCID 57352089 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-[2-(5-Ethyl-2-pyridinyl)-2-hydroxyethoxy]benzaldehyde | HCID 11550787 | 48.1% |
Reaction Steps
0.5 g (0.0023 mol) 5-ethyl-2-(2-oxo-[1,3,2]-dioxathiolan-4-yl)-pyridine was added into solution of 0.343 g (0.0027 mol) p-hydroxy benzaldehyde dissolved in 5 mL DMF. Reaction mixture was heated at 80° C. for 14 hr. Subsequent work up furnished 0.3 g (47%) the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07863300B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-d23bc44f2d264d6ca85c2a7fffd1f5c8 |
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| Source note | uspto-grants-2011_01 |
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