HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 250168Generated: October 30, 2026
4-Toluenesulfonyl chloride → HCID 73505384, compound
https://huagongshe.com/reaction/250168
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-[2-(5-Ethyl-2-pyridinyl)-2-hydroxyethoxy]benzaldehyde | HCID 11550787 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 73505384 | HCID 73505384 | — |
Reaction Steps
0.44 g (0.0044 mol) triethyl amine was added to a solution of 1 g (0.0036 mol) 4-[2-(5-ethyl-pyridin-2-yl)-2-hydroxy-ethoxy]-benzaldehyde and 0.7 g (0.0036 mol) tosyl chloride dissolved in 25 mL dichloromethane at 0-5° C. Reaction mixture was stirred at 0-5° C. for 4 hr. Progress of the reaction was monitored by TLC and after completion of reaction, substantial work-up in excess water yielded the desired product. Yield of the product was 1 g (70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07863300B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-be2dce30b75c4bd2a80125001f757cae |
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| Source note | uspto-grants-2011_01 |
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