4,4-Dimethylpent-1-yn-3-ol → 1-{4-[1-(4-Benzyloxy-3-methylphenyl)-1-ethylpropyl]-phenyl}-4,4-dimethylpent-1-YN-3-OL

Participants

Reaction Steps

In a manner similar to that described for Example 1D, but replacing 2-methyl-3-butyn-2-ol with 4,4-dimethylpent-1-yn-3-ol, the title compound was prepared from 5-[1-(4-bromophenyl)-1-ethylpropyl]-2-benzyloxytoluene: 1H-NMR (CDCl3) δ 7.44-7.48 (2H, m), 7.37-7.42 (2H, m), 7.31-7.36 (3H, m), 7.14 (2H, d, J=8.6), 6.94 (1H, dd, J=2.3, 8.3), 6.90 (1H, d, J=2.3), 6.79 (1H, d, J=8.3), 5.05 (2H, s), 2.22 (3H, s), 2.07 (4H, q, J=7.3), 1.07 (9H, s), 0.62 (6H, t, J=7.3).

Provenance & Evidence