Borane → HCID 58088520, compound

HRID 250197Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:4]=1[C:5]([CH:12]([C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1)[CH2:13][C:14]([NH:16][CH3:17])=O)=[CH:6][NH:7]2.B>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:4]=1[C:5]([CH:12]([C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1)[CH2:13][CH2:14][NH:16][CH3:17])=[CH:6][NH:7]2

Participants

Reactant 2

HCID 6331Borane

HCID 58088588HCID 58088588, compound

Product 1

HCID 58088520HCID 58088520, compound

Procedure

3-(4-methoxy-1H-indol-3-yl)-N-methyl-3-pyridin-4-yl-propionamide was reduced with borane using the procedure described in step 3 of Example 1 to afford [3-(4-methoxy-1H-indol-3-yl)-3-pyridin-4-yl-propyl]-methyl-amine, (M+H=296).

Sources & evidence

ORD record: ord-c74245de45384c469378bdf1ae1a0416
Source dataset: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07863305B2

Reaction notes

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