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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 250206Generated: November 2, 2026

Methylamine → (S)-[3-(4Chloro-indol-1-yl)-3-phenyl-propyl]-methyl-amine

https://huagongshe.com/reaction/250206

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant4-chloro-1-(3-chloro-1-phenyl-propyl)-1H-indoleHCID 67269106—
Product(S)-[3-(4Chloro-indol-1-yl)-3-phenyl-propyl]-methyl-amineHCID 58088492—

Reaction Steps

4-chloro-1-(3-chloro-1-phenyl-propyl)-1H-indole (0.228 g) was reacted with methylamine following the procedure of step 3 of Example 11 to afford 0.135 g of (S)-[3-(4Chloro-indol-1-yl)-3-phenyl-propyl]-methyl-amine, (M+H=300).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07863305B2
Source datasetuspto-grants-2011_01
ORD IDord-515d6bd20b19426fac7345228952f0b3
Source noteuspto-grants-2011_01