Methyl 2-aminoisobutyrate hydrochloride → HCID 11372033, compound

HRID 250313Notes

Reaction equation

HRID 250313 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH:13]([CH3:15])[CH3:14])=[CH:9][CH:10]=2)[C:5]([OH:16])=[C:4]([C:17]([OH:19])=O)[N:3]=1.Cl.C[O:22][C:23](=[O:28])[C:24]([NH2:27])([CH3:26])[CH3:25]>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH:13]([CH3:14])[CH3:15])=[CH:9][CH:10]=2)[C:5]([OH:16])=[C:4]([C:17]([NH:27][C:24]([CH3:26])([CH3:25])[C:23]([OH:28])=[O:22])=[O:19])[N:3]=1

Participants

3

Reactant 2

HCID 13258034Methyl 2-aminoisobutyrate hydrochlorideHCID 542422501-Chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carboxylic acid

Product 1

HCID 11372033HCID 11372033, compound

Procedure

Prepared in analogy to Example A-1 a) and b) from 1-chloro-4-hydroxy-6-isopropoxy-isoquinoline-3-carboxylic acid (can be obtained according to U.S. Pat. No. 6,093,730, October 1998, Weidmann et al.) and 2-amino-2-methyl-propionic acid methyl ester hydrochloride; MS-(+)-ion: M+1=367.0 amu.

Workup

  1. customcan be obtained

Sources & evidence

ORD record
ord-dc015b6beb1d4a32941f23b62eeafc0d
Source dataset
uspto-grants-2011_01
Patent number
US07863292B2

Reaction notes

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