HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
methyl D-alaninate → (R)-2-[(7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-propionic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | methyl D-alaninate | HCID 89020 | — |
| Edukt | 7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid | HCID 18698130 | — |
| Produkt | (R)-2-[(7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-propionic acid methyl ester | HCID 86595455 | — |
Reaktionsschritte
7-Benzyloxy-1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid, 0.33 g, was coupled with D-Alanine methyl ester analogously to Example A-1 a). 0.246 g of off-white solid were obtained: MS-(+)-ion, M+1=415.0 amu.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07863292B2 |
| Quelldatensatz | uspto-grants-2011_01 |
| ORD ID | ord-ba3e7e8a49d54e4ab2b6652c91626579 |
| Quellennotiz | uspto-grants-2011_01 |