7-Benzenesulfinyl-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester → [(7-Benzenesulfinyl-4-hydroxy-isoquinoline-3-carbonyl)-amino]-acetic acid

HRID 250463Notes

Reaction equation

HRID 250463 reaction equation
C(O[C:6]([C:8]1[N:9]=[CH:10][C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][CH:14]=[C:13]([S:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:20])[CH:12]=2)=[O:7])CCC.C1CC2N(C3C=C(C=C(C4C=CC=CC=4)C4C=CC=CC=4)C=CC=3)C3C(C2C1)=C(/C=C1/C([N:43]([CH2:47][C:48]([OH:50])=[O:49])C(S/1)=S)=O)C=CC=3>>[C:21]1([S:19]([C:13]2[CH:12]=[C:11]3[C:16]([C:17]([OH:18])=[C:8]([C:6]([NH:43][CH2:47][C:48]([OH:50])=[O:49])=[O:7])[N:9]=[CH:10]3)=[CH:15][CH:14]=2)=[O:20])[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 667130707-Benzenesulfinyl-4-hydroxy-isoquinoline-3-carboxylic acid butyl esterHCID 102186406D-102 (FDA NDC: 58264-0108)

Product 1

HCID 11451528[(7-Benzenesulfinyl-4-hydroxy-isoquinoline-3-carbonyl)-amino]-acetic acid

Procedure

Prepared in analogy to Example D-1 g) from 7-benzenesulfinyl-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester (Compound D-102 A). MS-(+)-ion: M+1=371.1.

Sources & evidence

ORD record
ord-e06d3fe6efcf46d398dc1bae8333bbb3
Source dataset
uspto-grants-2011_01
Patent number
US07863292B2

Reaction notes

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