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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 250469Generated: October 25, 2026

4-Methylbenzenethiol → [(4-Hydroxy-1-p-tolylsulfanyl-isoquinoline-3-carbonyl)-amino]-acetic acid

https://huagongshe.com/reaction/250469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzenethiolHCID 7811—
ReactantFG-2216HCID 6914666—
Product[(4-Hydroxy-1-p-tolylsulfanyl-isoquinoline-3-carbonyl)-amino]-acetic acidHCID 11360648—

Reaction Steps

The title compound was prepared from [(1-chloro-4-hydroxy-isoquinoline-3-carbonyl)-amino]-acetic acid (U.S. Pat. No. 6,093,730) and 4-methylbenzenethiol under conditions analogous to Example D-110; MS (−) m/z 367.09 (M−1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07863292B2
Source datasetuspto-grants-2011_01
ORD IDord-abccd997c15341239e054b9df9cba96e
Source noteuspto-grants-2011_01